PPARD monoclonal antibody (M03), clone 1G4
产品名称: PPARD monoclonal antibody (M03), clone 1G4
英文名称: PPARD monoclonal antibody (M03), clone 1G4
产品编号: H00005467-M03
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant PPARD.
- Immunogen:
- PPARD (NP_006229, 56 a.a. ~ 165 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- DQLQMGCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEG
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Cell lysate)
- PPARD monoclonal antibody (M03), clone 1G4 Western Blot analysis of PPARD expression in K-562 ( Cat # L009V1 ).
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged PPARD is approximately 0.1ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 5467
- GeneBank Accession#:
- NM_006238
- Protein Accession#:
- NP_006229
- Gene Name:
- PPARD
- Gene Alias:
- FAAR,MGC3931,NR1C2,NUC1,NUCI,NUCII,PPAR-beta,PPARB
- Gene Description:
- peroxisome proliferator-activated receptor delta
- Omim ID:
- 600409
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation. [provided by RefSeq
- Other Designations:
- OTTHUMP00000016256,nuclear hormone receptor 1,peroxisome proliferative activated receptor, delta
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